Transperineal prostate biopsy
The safest, most effective and best tolerated approach to diagnosing prostate cancer.
Understanding prostate biopsy
A prostate biopsy obtains small samples of prostate tissue. It is the only way to accurately diagnose prostate cancer. There are two techniques: transrectal and transperineal.
Through the rectum
A needle is passed into the prostate through the rectal wall. Because the rectum contains stool and bacteria, this approach carries significant risks.
- Higher infection risk. About 2 to 4%, including sepsis, which is rare but serious.
- Antibiotics required. Patients take antibiotics for several days around the biopsy.
- More discomfort. Many patients report greater discomfort during and after the procedure.
- More complications. Some patients have prolonged rectal bleeding.
Through the skin
A needle is passed into the prostate through the skin between the scrotum and the anus, avoiding the rectum.
- Lower risk of infection. The rectal passage, which can introduce bacteria, is avoided.
- Higher diagnostic yield. More complete sampling and higher detection of clinically significant cancer.
- More comfortable. Many patients find it more tolerable.
- Fewer complications. Fewer severe complications, such as significant rectal bleeding.
Would you prefer a transperineal biopsy?
Transperineal prostate biopsy requires a referral from a urologist or oncologist. For a suspicion of prostate cancer, any physician may refer to one of our urologists, or to the Prostate Diagnostic Assessment Clinic at Scarborough Health Network.